
April 2017
“Amhion” company congratulates our scientific consultant and one of the company founders, Doctor of Sciences, Professor, Shtilman Mikhail Isaakovich on his 80th anniversary!More
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February 2016
“Amhion” company together with Medical faculty of Otto von Guericke
Magdeburg University (Germany), “Arivis” (Germany), “ToxPlus” (Greece)
and “Drugs Technology” (Russia) started international project NABUCO:
“Nanoparticles for Brain Use, Diagnostic and Ophthalmological
Applications” organized in frames of ERANET RUS PLUS program.More
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December 2015
Our company wishes you a Happy New Year! On behalf of all employees
wish you prosperity and happiness in the New Year and good health
and success in all your deeds!More
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Phone: |
(499) 972-48-08 |
Fax: |
(495) 609-29-64 |
E-mail: |
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 «Amphion
Research and Production Centre» LLC specializes in research and
development of new polymer materials for medical and biological use.
Our main lines of research are:
1) Creation of new high-performance nanoscale forms of
biologically active and medical substances
The
products that we develop are nanoscale spherical containers based on
non-hazardous biocompatible polymers that can be loaded with various
biologically active and medical substances.
These delivery systems developed by our specialists provide a new
means of introducing drugs into the body alongside more traditional
solutions (pills, capsules, ointments, creams, suppositories).
Our polymer nanoparticles have a higher capability for penetration
of body barriers and cellular membranes and targeted delivery of
drugs to damaged organs, tissues and cells.
New nanoscale containers guarantee the desired effective
concentration and therapeutic dose of inserted bio-active substance
for a long period of time, which allows to decrease the number of
introductions of the drug into the body, reduce the quantity of
active substance and to shorten the period of treatment.
Polymer nanoparticles ensure direct, targeted delivery of bio-active
substance into the selected area (affected region), bypassing other
body parts and avoiding systemic exposure of the organism to the
bio-active substance and its side effects.
Moreover the use of polymer nanocarriers allows to create
hydrocompatible forms of advanced and highly efficient bio-active
substances whose use was formerly limited or impossible due to their
poor solubility in water.
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2) New medical and bio-tech materials based on porous polymer
hydrogels

Porous hydrogel materials developed by our company can be used for
creating soft tissue replacement implants, wound dressings, systems
with controlled drug discharge and matrixes for tissue engineering.
Our materials are characterized by high biocompatibility,
biodegradability, stimulation of regeneration processes, high
sorbing capacity, stability and a range of other features, that
allow to use them as a basis for developing medical devices superior
to all the currently existing analogues, while at the same time
keeping the production cost at a much lower level.
We are currently preparing for production two products based on
“MM-Gel” porous hydrogel material:
- “MM-Gel-R” wound dressing developed for
effective treatment of wounds, ulcers, burns,
freeze-burns and bed sores of various etiology, skin
defects and areas of donor skin harvesting, as well
as for replacement of skin grafts. The distinctive
feature of our wound dressing is that it can be used
at any phase of wound treatment.
- “MM-Gel-F” surgical implant, developed to fill
post-surgical cavities and soft tissue defects, for
example in surgery or cosmetology. The implant
stimulates reparation process in the wound area,
fully degrades into harmless products and gets
substituted by tissue in several months. The
material has good adhesion to the surface, takes the
form of the defect and remains stable under standard
sterilization procedures.
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3) Medical and biotech polymers with own biological activity
For a number of years "Amphion RPC" has been working in
cooperation with “Biomaterials” Academic Centre of the D. Mendeleev
University of Chemical Technology of Russia on the development of
conceptually new medical devices, as well as biotech and
agricultural products – polymer materials with their own biological
activity.
Our studies resulted in the development of two big bioactive
polymer groups:
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À) Phytoactive polymers – polymer derivatives of
plant growth and development regulators, that can boast a
comprehensive range of unique features:
- High-level
activity at low
dosage;
- Prolonged
action;
- Lower risk of
overdose;
- No hazard to
human health;
- Resistance to
incidental loss of
active agent;
- Optimal
solubility in water.
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B) Immunostimulating polymers – polymer derivatives of natural
aminoacids possessing high-level immunostimulating action, while
enhancing the production of interferon and suppressing replication
of microorganisms under the effect of antibiotics. These polymers
can be used as:
- Components for
new safe blood
substitutes;
- Immunostimulants
that decrease the
decease and recovery
period.
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